Cormorant Pharmaceuticals is a newly founded biopharmaceutical company specializing in the development of innovative medicines for diseases with a large unmet medical need.

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Test tubes

Our Product

Our first product in development is HuMax-IL8,  a medicine that inhibits the effects of interleukin 8 (IL-8), a chemokine that was recently shown to be an important target for cancer stem cells in several cancers, including breast, colorectal and liver cancer. We have a partnership with Genmab for HuMax-IL8 and we anticipate this will be our first product in the clinic.

Read more about cancer stem cells and IL-8 and HuMax-IL8.


Interleukin-8 is a factor that has been shown to be involved in the progression of many cancer forms by stimulating cancer growth, angiogensis and metastais. Recent research has also shown that IL-8 plays an important role in epithelial mesenchymal transition (EMT) as well as cancer stem cell renewal.

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Present day

Cancer treatment outcomes have improved substantially over the last decades, but many forms of cancer are still incurable if detected too late. There is a large medical need for improved therapies for those patients. Targeting cancer stem cells holds up the potential to improve on current treatment outcomes by reducing the risk of treatment failure and recurrence of the disease.

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Our solution

With our first Product in development, HuMax-IL8, we are targeting cancer spread and cancer stem cells. HuMax-IL8 is a fully human antibody targeting interleukin-8. The antibody binds IL-8 with high affinity and specificity and has been through pre-clinical dvelopment as well as a phase I/II trial in patients.

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Our vision

Our vision for HuMax-IL8 is that the inhibition of IL-8 will target the aggressive behaviour of cancer cells and cancer stem cells in several cancer forms. This will then increase the efficacy of existing cancer therapies as well as reduce the resistance to them. This will in turn lead to better disease control and fewer recurrencies.

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Recent stories


IL-8 signaling involved in tumor immunosuppression – new study shows

  A paper published recently in Science Translational Medicine has elegantly shown that upregulated IL-8 signaling is involved in protecting tumors from the immune system. The tumors seem to be able to produce IL-8 in large quantities in pediatric patients with sarcoma. Immune suppression is achieved by the tumors in different ways, but the mechanism mediated […]

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New research collaboration with Genmab

Stockholm May 7, 2014. Cormorant Pharmaceuticals has entered a research collaboration with Genmab to evaluate their DuoBody technology for the creation of a bispecific antibody against IL-8 and an undisclosed target. IL-8 has been shown to be up-regulated upon treatment with and to confer treatment resistance to a number of different targeted therapies. This research […]

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